- Coxiella burnettii is highly infectious by the aerosol route.
- Q-Fever is rarely transmitted from person to person.
- Incubation period is 10-40 days.
- Acute infection may be asymptomatic or a self-limited febrile illness.
- Chest x-ray evidence of pneumonia is present in up to 50% of cases.
- Mortality rate is less than 2%.
- Requires serologic confirmation (IFA or ELISA)
- Isolation of organism is not recommended due to significant hazards from handling bacterial cultures in the laboratory
- Universal precautions. Patients do not require isolation rooms.
- Illness usually resolves without treatment.
- Tetracyclines are the antibiotics of choice for more severe illnesses.
- Tetracycline antibiotics are very effective if administered 8-12 days AFTER exposure.
- Starting prophylaxis immediately after exposure can delay symptom onset but does not prevent illness.
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